How Can Custom Cleanroom Designs Adapt to My Industry’s Requirements?

How Can Custom Cleanroom Designs Adapt to My Industry’s Requirements?

by | Oct 31, 2023 | Aerospace Cleanrooms, Cleanroom Design, Pharmaceutical Cleanrooms

In today’s world, cleanliness isn’t just a virtue – it’s a necessity. Here at Angstrom Technology, we’re experts in tailoring cleanrooms to meet the unique needs of various industrial applications. From automotive to life sciences and beyond, we’ll explore how custom cleanroom designs can be implemented to meet industry requirements and keep businesses thriving. 

Discover the Vital Role of Cleanroom Designs

Cleanrooms are controlled environments engineered to minimize contamination from particles, microorganisms, and other impurities by precisely regulating air quality, temperature, humidity, and pressure. Achieving this level of control requires meticulous design, construction, and ongoing maintenance. 

Cleanrooms are implemented in a wide array of industries, ranging from pharmaceuticals to aerospace. In some fields, the tiniest of particles or microbes can lead to product defects or health hazards, so cleanrooms have become an invaluable tool.

The need for custom cleanroom designs tailored to industry-specific requirements cannot be overstated. Each sector presents unique challenges, including stringent cleanliness standards and specific regulations. Therefore, a one-size-fits-all approach does not suffice when it comes to cleanrooms. 

Attempting to apply a uniform design to vastly different industries risks compromising the quality and safety of products and can result in regulatory non-compliance. Custom cleanroom designs address these challenges head-on by adapting to the precise needs of each industry. 

To learn more about specific cleanroom classifications and standards, check out our helpful Classifications & Standards page. 

Cleanroom Designs Across Popular Industries:

At Angstrom Technology, we offer dynamic and flexible cleanroom designs, ensuring that your environment aligns seamlessly with the objectives and standards of your industry. We utilize custom designs so you can achieve the highest level of cleanliness, precision, and product integrity. 

Below, we will showcase some of the most popular sectors we work with when creating custom modular cleanrooms. Don’t your field? No worries! We work with many companies that differ from what’s listed below. Email or call our team and discover what we can do for you. 

Pharmaceuticals

The pharmaceutical industry relies heavily on cleanrooms for drug manufacturing and research. Sterile environments are paramount to ensure product safety and regulatory compliance.

pharmaceutical cleanroom projectPharmaceutical cleanrooms must adhere to stringent regulations. The industry requires cleanliness down to the molecular level to ensure drug purity and patient safety.

Angstrom Technology Custom Cleanroom Solutions for the Pharmaceutical Industry:

The pharmaceutical industry is subject to heavy government regulation, and pharmaceutical cleanrooms must meet stringent cGMP standards and requirements. You can be assured that Angstrom Technology designs, constructs, and installs the highest-quality pharmaceutical cleanrooms in the business. 

Automotive

In the automotive sector, cleanrooms are indispensable for manufacturing sensitive components. Precision is the name of the game, as even a speck of dust can impact the performance of critical parts.

automotive projectAutomotive cleanrooms must accommodate a variety of components, from delicate electronic systems to robust engine parts. Each type of component presents its unique contamination challenges.

Angstrom Technology Custom Cleanroom Solutions for the Automotive Industry:

Angstrom Technology designs, builds, and installs top-of-the-line cleanrooms to meet the needs of the automotive industry. Our automotive cleanrooms can meet any classification requirements and are ideally suited for automotive innovation, component manufacturing, and quality testing applications.

Aerospace

Aerospace companies utilize cleanrooms for the production of aircraft components. The slightest impurity could compromise the structural integrity of these parts and have massive effects on production.

aerospace projectAerospace cleanrooms must always meet the regulated levels of the industry. The challenge is maintaining cleanliness while dealing with large and complex parts, as even a tiny defect could have catastrophic consequences.

Angstrom Technology Custom Cleanroom Solutions for the Aerospace Industry:

When it comes to the rigorous cleanroom classifications of the aerospace industry, Angstrom Technology creates the best modular cleanrooms available. All of our cleanroom builds comply with US building and safety codes and are complete with the fixtures and systems you need to use right away. 

Cell and Gene Therapy

A one-size-fits-all approach to cleanrooms drastically falls short when dealing with the intricacies of cell and gene therapy. These revolutionary therapies involve manipulating and administering living cells and genetic materials, making the need for pristine, contamination-free environments paramount. 

Cell and gene therapy have their own distinct set of requirements, including the need for ultra-sterile conditions to ensure patient safety and therapy effectiveness. Custom cleanrooms are designed to tailor to this innovative field’s stringent standards and specialized needs, thereby playing a crucial role in advancing life-saving treatments and ensuring regulatory compliance.

Angstrom Technology Custom Cleanroom Solutions for the Cell and Gene Therapy Industry:

Cell and gene therapies require complex production processes requiring cellular engineering, genetic engineering, growth, and purification. All these operations must be carried out in a controlled environment to ensure safe, reliable, and repeatable results. You can be sure that our cleanrooms meet all the necessary ISO classification requirements. 

Life Sciences

Life sciences is a multifaceted field encompassing many applications, from biotechnology and medical device manufacturing to research and development in genetics and microbiology. Cleanrooms play a pivotal role in maintaining the integrity and innovation of this industry.

biopharma cleanroomCustom cleanrooms provide tailored solutions to cater to the unique needs of each life sciences subsector. They ensure that the environment is precisely aligned with the industry’s specific cleanliness, safety, and operational standards, thereby facilitating groundbreaking research, the production of life-saving therapies, and the advancement of knowledge in the life sciences field.

Angstrom Technology Custom Cleanroom Solutions for the Life Sciences Industry:

The Angstrom Technology Life Sciences Division (ATLSD) has quickly emerged as a leader in cutting-edge products and services for cleanrooms, dry rooms, and cold rooms. We’re dedicated to pushing the boundaries of what’s achievable in the industry, focusing on how integrated teams can provide the best project approach for compliance and success.

Partner with Angstrom Technology for Your Industry-Specific Cleanroom Needs

If you’re seeking tailored cleanroom solutions for your industry, Angstrom Technology is ready to be your dedicated partner in crafting contamination-free environments. Our proven expertise in custom cleanroom designs spans various sectors, ensuring compliance, precision, and product integrity. 

Don’t compromise when it comes to the cleanliness and safety of your operations. Reach out to Angstrom Technology today and discover how we can help you meet your industry-specific cleanroom needs!

Do You Know the Difference Between Negative Pressure vs. Positive Pressure Cleanrooms?

Do You Know the Difference Between Negative Pressure vs. Positive Pressure Cleanrooms?

by | Oct 26, 2023 | Air Circulation, Cleanrooms

In today’s fast-paced world of technology, pressurized cleanrooms are being utilized in more and more industries and applications. Two main types of cleanrooms are negative pressure rooms and positive pressure rooms. 

The level of pressure determines the way air naturally moves in a space. High and low, or positive and negative, pressure can be used as tools in cleanroom environments to help cleanrooms reach their required classifications.

Negative Pressure vs. Positive Pressure Cleanrooms

Let’s dive deeper, learn the difference between negative pressure vs. positive pressure cleanrooms, and discover how they work. 

How Does Air Pressure in Cleanrooms Work?

Air naturally flows from areas of high pressure to areas of low pressure. Examples of this are found around us every day. For example, wind and weather are formed from the uneven heating of the earth’s surface, which generates pockets of high and low pressure air. 

Have you ever witnessed the sudden closing of a door as air is sucked out of a room even though there’s no breeze? This experience is high pressure air moving to a low pressure area to achieve stasis. 

Another example of this process is when air escapes from a balloon. The air travels from a high pressure environment to the relatively low pressure of the surrounding air. 

What happens in all of these situations is that when air is moving in one direction, it’s not moving in the opposite direction. When air is moving out of the balloon, air isn’t also moving into the balloon, as long as the air inside the balloon is more pressurized. 

This concept can be applied to cleanrooms to stop airflow into a cleanroom or out of it, limiting particle transfer via the air and maintaining a cleaner environment.

To put this as simply as possible:

Higher pressure air within a cleanroom (compared to the air outside the room) blocks contaminants from entering the cleanroom, as air naturally wants to flow out. Conversely, lower pressure air within a cleanroom can trap contaminants and prevent them from leaving a cleanroom, as the natural flow of air wants to move in. 

Using Positive and Negative Pressure in Cleanroom Design

Using pressure in cleanrooms, either high pressure (positive pressure) or low pressure (negative pressure), can benefit many cleanroom applications, but how do you implement it in the cleanroom design?

Cleanroom pressure is achieved by controlling how much air is put into the cleanroom and how much is withdrawn. 

In a positive pressure cleanroom, filtered air is consistently pumped into the room through the HEPA filtration and cleanroom HVAC system. If a door or window were opened in the cleanroom, air would rush out into the outside environment. This positive pressure ensures that the products and processes within the cleanroom are protected in the event of a breach or leak. Because the cleanroom has positive pressure, the air is forced out of the cleanroom, preventing contaminated or unfiltered air from seeping in. 

To achieve negative air pressure, external exhausts pull air from the cleanroom at a faster rate than air is introduced over a span of time. The resulting negative pressure means the air will want to flow into the cleanroom to fill the low pressure area, effectively stopping contaminants from going against that natural movement to escape the cleanroom.

To maintain positive or negative pressure in cleanrooms, adjacent spaces must be maintained at a lower or higher pressure than that of the cleanroom. If you implement a pressurization system into your cleanroom design, a pressure monitoring system is vital to ensure balance and consistency. The monitoring system will check and maintain consistent pressure, which can be adjusted manually or automatically.

Positive PRESSURE CLEANROOM APPLICATIONS:

High pressure, or positive pressure rooms are beneficial in applications where the slightest particle interference could disrupt processes within the cleanroom. 

Semiconductor cleanrooms, microprocessor cleanrooms, and aerospace and defense cleanrooms are examples of industries that benefit from positive pressure cleanrooms, as they are highly averse to contaminating particles. Medical cleanrooms also use positive pressure to protect sensitive patients and maintain a controlled space.

Even when the stakes aren’t as high, using slightly positive pressure in cleanrooms can help reach cleanroom classifications and maintain an overall cleaner environment.

negative PRESSURE CLEANROOM APPLICATIONS:

Low pressure cleanrooms, or negative pressure rooms, are ideal for applications that need to isolate substances, particles, or fumes inside the cleanroom environment to protect the space outside. They are widely used in medical cleanrooms for research, testing, and the development of treatments using sensitive substances. 

Pharmaceutical applications also use negative pressure in cleanrooms as part of a segmented layout. One room is kept at a lower pressure, while the anteroom immediately outside is maintained at a slightly higher pressure. This allows employees to transition into the negative pressure room with minimized disruption.

Need Help Choosing the Right Cleanroom Pressure? Angstrom Technology Can Help

Using the natural air movement due to pressure, we can build safer, more effective cleanrooms. Positive and negative pressure cleanrooms can protect against entering contaminants (in positive pressure cleanrooms) or contaminant leakage (in negative pressure cleanrooms). 

Which cleanroom pressure best suits your needs? At Angstrom Technology, we’re here to guide you. Our dedicated cleanroom experts are ready to precisely tailor airflow patterns and containment solutions for your unique application. Get in touch with us today for expert assistance in creating the ideal cleanroom environment for your specific requirements.

Get Instant Access to Our Cleanroom Design Guide

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Quicker, Cleaner And Less Costly: The Benefits Of Modular Clean Rooms

Quicker, Cleaner And Less Costly: The Benefits Of Modular Clean Rooms

by | Oct 25, 2023 | Press Releases

PRESS RELEASE

[Grand Rapids, MI] —The demand for life sciences facilities is holding strong across the U.S. and is still well above where it was prior to the pandemic. The rise of these facilities has created a demand for another type of space: modular clean rooms.

Clean rooms are controlled environments that filter out pollutants like dust, airborne microbes and aerosol particles. Market Research Future this year reported the clean room technology market is projected to grow from $4.9B in 2022 to $6.9B by 2030.

These spaces can be crucial to the success of life sciences facilities, and they need to be built quickly and efficiently by firms that understand their importance.

Angstrom Technology began designing and selling clean rooms in Michigan in 1989. Today, the company installs and distributes clean rooms to facilities around the globe. Owner and CEO Matt Isard said he believes the most effective way to quickly install clean rooms that are flexible and compliant with today’s rapidly changing life sciences companies is to embrace modular construction.

“Modular rooms give the customer the versatility to add, subtract and relocate as your needs change, with minimal disruption to your process,” Isard said. “Additionally, the overall cost of a modular structure is lower than that of a conventional building, and it cuts construction and installation time down significantly.”

Angstrom Technology has launched a life sciences division, , focused on delivering modern systems, products and services for clean rooms and humidity-controlled dry rooms in the life sciences sector. Bisnow sat down with Isard and President Jennifer Biro to learn more about the benefits of modular clean rooms and the company’s plans for its new division.

Bisnow: What are some of the main benefits of choosing to use modular clean rooms?

Isard: The benefits can be broken down into five main categories: time, cleanliness, cost, tax deductions and versatility. Modular construction takes less time than other build processes, allowing a room to be up and running faster. They are also cleaner because there is less cutting, drilling and other work getting done on-site that can add dust and other contaminants to the air.

Additionally, all the design, engineering and manufacturing work for a modular clean room falls under one bill to keep expenses low. On top of those cost savings, a modular system is considered capital equipment and can be depreciated quicker — at around seven years — compared to traditional real estate that depreciates at 39 years.

Finally, as the life sciences sector changes and grows from contract development manufacturing organizations to cell, gene, mRNA and more, clients need the highest level of service, optionality, compliance expertise, quality and safety protocols. Modular construction allows for greater flexibility with minimal disruption to a facility’s workflow, ensuring schedule and costs are kept in line.

Bisnow: Can you tell me more about Angstrom Technology and your level of experience with these projects?

Isard: Angstrom Technology brings 34 years of experience as a turnkey provider of clean rooms, dry rooms and cold rooms to every project. Our technical team serves a wide range of sectors, including life sciences, healthcare, medical device, automotive, aerospace/defense, microelectronics, injection molding, food and beverage, EV dry room, current good manufacturing process, cell and gene therapy, and veterinary science.

We execute successful and compliant projects for clients both nationally and globally. We have offices in Grand Rapids, Michigan; Irvine, California; and Conshohocken, Pennsylvania. We also have offices in the UK, including York, Lancaster, High Wycombe and Newcastle and serve clients throughout North America, South America, Europe, the Middle East and Singapore.

Bisnow: What changes have you noticed in customer expectations or priorities in the years since Angstrom was founded?

Isard: Customers in the clean room industry are increasingly seeking turnkey services from collaborative providers who can manage the entire project, from design to implementation to validation.

While many of our clients are well-versed in clean rooms, we make the entire process relatable by offering practical, solution-based approaches that align with stakeholders’ needs. We also recognize that different industries may require different technical approaches and need options in system choices, so we have in-house technical experts to specifically address compliance, ISO levels, GMP and cGMP, or current good manufacturing practices. They can also address cell and gene therapy, contract development and manufacturing organization, dry rooms and environmentally controlled rooms.

Bisnow: Could you tell us more about Angstrom’s life sciences division and how you are addressing this trend?

Isard: Angstrom Life Sciences is a specialized division that focuses on cutting-edge systems, products and services for clean rooms, dry rooms and all temperature or environmentally controlled rooms. Being able to offer clients a multitude of options for their project needs and requirements is a real differentiator for this division. We have the most choices at every price point and every necessity required. We believe that providing clients with striated solutions, estimates and schedules they can trust with the utmost integrity is something to be proud of.

We promote a collaborative client experience by tailoring solutions to individual client needs rather than being constrained by specific product offerings. We maintain objectivity by not producing our own panels, allowing for a truly cooperative and unbiased approach.

Bisnow: What is Angstrom’s capability regarding global sourcing?

Isard: We are both a national and global company, with the capability to source materials and provide design-assist, installation, commissioning and validation services worldwide. This ensures that projects are executed safely, with high-quality standards and in full compliance with industry requirements.

This article was produced in collaboration between Angstrom Technology and Studio B.

Media Contact:
Maria Valgenti
610-340-8769
maría.valgenti@angstromtech.com

Angstrom Technology Launches New Life Sciences Division, Elevating Expert Technical Services, Highest Level of Choices and Quality

Angstrom Technology Launches New Life Sciences Division, Elevating Expert Technical Services, Highest Level of Choices and Quality

by | Oct 9, 2023 | Press Releases

PRESS RELEASE

 

[Philadelphia, PA] — Angstrom Technology, a trusted leader in providing expert technical services for
over 30 years, is proud to announce the launch of its new Life Sciences Division. This strategic move
comes as a response to the growing demand for high-quality services in the life sciences industry and is a
testament to Angstrom Technology’s commitment to exceeding client expectations.

 

Building upon three decades of successful and compliant projects, the Life Sciences Division is dedicated
to delivering the highest level of technical expertise, client satisfaction, transparency, and flexibility while
upholding the company’s core values of integrity and quality. Jennifer Biro, President, joins the
established team to lead the Life Sciences Division. Angstrom Technology recognizes the critical nature
of cleanrooms, dry rooms, and cold rooms in the life sciences and technical sectors and is poised to
provide turnkey solutions with the most optionality that set industry standards.

 

Key Highlights of Angstrom Technology’s Life Sciences Division:

 

Unmatched Expertise: With a team of experienced professionals, Angstrom Technology’s Life Sciences
Division brings a wealth of knowledge and expertise to every project. Clients can rely on a team that
understands the unique challenges and requirements of the most technical of projects with schedule
and cost in mind. From initial concept and design to material choices, installation, commissioning, and
validation, Angstrom Technology offers a comprehensive suite of custom products and services.

 

Client-Centric Approach: Customer satisfaction is at the forefront of Angstrom Technology’s mission.
The Life Sciences Division is committed to working closely with clients to find solutions that meet their
specific needs, ensuring that every project is a success. By offering a multitude of system and product
choices, nothing is one size fits all.

 

Flexibility and Adaptability: In a rapidly evolving industry, flexibility is key. Angstrom Technology’s Life
Sciences Division is equipped to adapt to changing project requirements and industry regulations,
providing clients with peace of mind with compliance experts in-house, no matter the industry.

 

Integrity, Safety, and Quality: Angstrom Technology has built a reputation for uncompromising integrity
and exceptional quality in its services and execution. With an EMR of 0.80, skilled tradespeople go home
safely at the end of the day. The Life Sciences Division continues to uphold these values and strives to
extend these services to clients globally.

 

Karan Rai, Chairman of the Board at Angstrom, and Managing Partner at private equity firm ASGARD
Partners expressed excitement about the launch of the Life Sciences Division, saying, “Our customers
have made it clear that they want us to have a more pronounced and focused presence in the Life
Sciences markets and that is exactly what we are building. We are fully committed to supporting the
company with all investments and resources required to deliver the best design and build technical
expertise and customer service to our Life Sciences clients. We are going to be a major player in this
space and are building a world-class team which starts with bringing Jennifer Biro on board as President
to lead this new division.”

 

As Angstrom Technology’s Life Sciences Division takes its first steps, it does so with a strong foundation
of experience, dedication, and a clear vision for the future. For more information about Angstrom
Technology and its Life Sciences Division, please visit www.angstromlifesciences.com.

 

About Angstrom Technology
Angstrom Technology is a respected leader in providing expert technical services for cleanrooms, dry
rooms, and cold rooms. With over 30 years of experience, the company is known for its flexibility,
optionality, commitment to quality, integrity, and client satisfaction. Angstrom Technology’s Life Sciences
Division is dedicated to delivering the highest level of expertise and turnkey solutions for the life
sciences, healthcare, microelectronics, battery, medical device, and technical market sectors.

 

Media Contact:
Maria Valgenti
610-340-8769
maría.valgenti@angstromtech.com

Angstrom Technology Completes Azzur Cleanrooms on Demand™ Raleigh facility

Angstrom Technology Completes Azzur Cleanrooms on Demand™ Raleigh facility

by | Jul 7, 2023 | Pharmaceutical Cleanrooms

Azzur Group appointed Angstrom Technology to build its latest Cleanrooms on Demand™ (COD) Raleigh facility in Morrisville, NC. Azzur Cleanrooms on Demand™ offers a hybrid early-phase manufacturing model. Early-phase manufacturers face specific challenges when starting up and scaling out. COD can remove barriers, such as the need for clinical manufacturing capability and lengthy facility design-build timeframes. Morrisville is minutes from the celebrated Research Triangle area of North Carolina, making it a prime location for this new state-of-the-art facility.

The 24,000 square foot Cleanrooms on Demand™ Raleigh facility features 24 independent cleanroom suites each with a Material Airlock (MAL), Personnel Airlock (PAL), Cleanroom and Exit PAL.  Shared entry and exit corridors provide easy access to and from each cleanroom via the locker room and changing area near one end of the cleanroom.  On the opposite end of the cleanroom, material airlocks provide a path for large equipment to enter the suites via the GMP warehouse.  All cleanroom suites are controlled and monitored by advanced systems which are tied into the building management system.

Azzur Morrisville cleanroom render

Cleanrooms on Demand™ locations

Azzur Cleanrooms on Demand™ Raleigh is the first COD facility Angstrom has completed for the Azzur Group and the 4th in the Azzur COD group. In June, Angstrom attended its grand opening ceremony.

Azzur Group plans to open additional Cleanrooms on Demand facilities in locations across the U.S. over the next two years. Our global structure allows us to project manage builds in multiple locations. Consequently, Angstrom Technology is also under construction on Azzur COD facilities in Devens, MA, and Alameda, California.

At Angstrom Technology, we have the capability to deliver exceptional cleanroom installations. Working with us across multiple facilities provides consistency in cleanroom design, specification, monitoring, and validation. This approach generates efficiencies and drives value. Equally important, it instills confidence in the performance and reliability of your controlled environments.

SPEAK WITH THE EXPERTS AT ANGSTROM TECHNOLOGY

Angstrom Technology partners with the world’s leading contamination control brands so we can design, build, and install high-spec, turnkey cleanrooms to meet your critical requirements across the US and around the globe. Using proven design strategies and quality build systems, you can trust that your work and employees will always be protected.

Request a cleanroom quote today, or contact our team for more information.

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